Mohamadreza Baghaban Eslaminejad Ph.D.

Department of Stem Cells and Developmental Biology

Professor

Email: eslami@royaninstitute.org

Phone: +98 2122339928

CV: Eslaminejad CV 2017

Mohammadreza Baghaban Eslaminejad earned his PhD from Tarbiat Modares University, Tehran, Iran and joined Royan Institute in 2004. He founded the adult stem cell lab and started his research on mesenchymal stem cells. The aim of this lab was to utilize stem cells for treatment of orthopedic diseases, especially bone and cartilage defects. He has done research on various animal models such as mouse, rabbit and dog, the result of which has been published in 165 papers and 170 abstracts in national and international journals and conferences. Moreover, he has contributed in 15 international books by writing chapter and has wrote two national books. As of now, his research is focused on late stages of clinical trial for using stem cells to treat patients. Dr. Baghaban Eslaminejad has won numerous awards, including first prize in the seventh Royan International Research Award for Reproductive Biomedicine and Stem Cell, Tehran, Iran, September 2006; Distinguished Researcher award, Tehran, Iran, 2007; Selected researcher in Razi Medicine Festival in Novel Technologies section, Tehran, Iran, 2009; Selected as Excellent Researcher in the National Festival for Commemorating Distinguished Researchers, Tehran, Iran, November 2010.

The main goal of his research team is to find methods of utilizing mesenchymal stem cells to treat bone defects such as fractures, lack of bone alignment and healing untreatable cartilage defects such as arthritis and rheumatism. Current research topics in this team include:
– Basic research done on mesenchymal stem cells
– Obtaining mesenchymal stem cells from various sources, such as fat tissue, dental sources, blood and other tissues in order to find the best human source
– Tissue engineering done on bone and cartilage tissues using mesenchymal stem cells
– Experimental studies to restore bone and cartilage tissues in defective animal models
– Basic research done on dental stem cells
– Regenerating dental tissue and jaw bone using stem cells obtained from teeth and bone marrow

MSc Students:

Mahsa Ghorbaninazhad (MS.c. student)

Maryam Hossein Zadeh (MS.c. student)

Razieh Kafi (MS.c. student)

Maliheh Khademi Shirvan (MS.c. student)

Masoumeh Hashemi (MS.c. student)

Mohammad Zaer (MS.c. student)

PhD Students:

Fatemeh Javanmard (Ph.D student)

Seyed Amir Kamali (Ph.D student)

Arefeh Basiri (Ph.D student)

Nesa Fani (Ph.D student)

Davoud Nasrabadi (Ph.D student)

Sima Bordbar (Ph.D student)

Maryam Dehghan Nayeri (Ph.D student)

Shahrbanoo Jahangir (Ph.D student)

Behnosh Tayebi (Ph.D student)

Fatemeh Khodabandehlou (Ph.D student)

Nahid Nasiri (Ph.D student)

Selected Publications:

  1. Zarkesh I1, Ghanian MH2, Azami M3, Bagheri F4, Baharvand H5, Mohammadi J6, Eslaminejad .Facile synthesis of biphasic calcium phosphate microspheres with engineered surface topography for controlled delivery of drugs and proteins. Colloids Surf B Biointerfaces. 2017 Sep 1;157:223-232
  2. Taghiyar L1,2, Hesaraki M1, Sayahpour FA1, Satarian L1, Hosseini S1, Aghdami N1, Baghaban Eslaminejad M3. Msh homeobox 1 (Msx1)- and Msx2-overexpressing bone marrow-derived mesenchymal stem cells resemble blastema cells and enhance regeneration in mice. J Biol Chem. 2017 Jun 23;292(25):10520-10533
  3. Shamekhi MA1, Rabiee A2, Mirzadeh H3, Mahdavi H1, Mohebbi-Kalhori D4, Baghaban Eslaminejad M. Fabrication and characterization of hydrothermal cross-linked chitosan porous scaffolds for cartilage tissue engineering applications. Mater Sci Eng C Mater Biol Appl. 2017 Nov 1;80:532-542
  4. Jahanmard-Hosseinabadi F1, Amani-Tehran M2, Eslaminejad MB,Mathematical Modeling and Experimental Evaluation for the predication of single nanofiber modulus.J Mech Behav Biomed Mater. 2017 Dec 10;79:38-45.
  5. Taghiyar L1,2, Hosseini S1, Hesaraki M1, Azam Sayahpour F1, Aghdami N1, Baghaban Eslaminejad M.Isolation, Characterization and Osteogenic Potential of Mouse Digit Tip Blastema Cells in Comparison with Bone Marrow-Derived Mesenchymal Stem Cells In Vitro.Cell J. 2018 Jan;19(4):585-598
  6. “Mousavi SN1, Koohdani F1, Shidfar F2, Eslaminejad MB3, Izadi P4, Eshraghian M5, Shafieineek L6, Tohidinik H.Effects of Maternal Isocaloric Diet Containing Different Amounts of Soy Oil and Extra Virgin Olive Oil on Weight, Serum Glucose, and Lipid Profile of Female Mice Offspring.Iran J Med Sci. 2017 Mar;42(2):161-169″
  7. Karamzadeh R1, Baghaban Eslaminejad M1, Sharifi-Zarchi A.Comparative In Vitro Evaluation of Human Dental Pulp and Follicle Stem Cell Commitment.Cell J. 2017 Winter;18(4):609-618. Epub 2016 Sep 26.”
  8. Aghajanpoor M1, Hashemi-Najafabadi S1, Baghaban-Eslaminejad M2, Bagheri F3, Mohammad Mousavi S3, Azam Sayyahpour F.The effect of increasing the pore size of nanofibrous scaffolds on the osteogenic cell culture using a combination of sacrificial agent electrospinning and ultrasonication. J Biomed Mater Res A. 2017 Jul;105(7):1887-1899.