Parvaneh Mohammadi Ph.D.

Department of Stem Cells and Developmental Biology

Assistant professor

Parvaneh Mohammadi earned her B. Sc. in Animal Biology from Shahid Chamran University of Ahvaz, Iran in 2006, and also, she graduated in MSc of developmental biology from Science and Culture University, Tehran, Iran, 2009. Upon completion of her Master’s degree, she continued her research as a research assistant at Royan Institute, in the Department of Regenerative Medicine and she started research on skin and hair field. In 2010 she got accepted as a PhD student in the Department of Cell and Developmental Biology at Royan Institute where she thereafter began a series of studies with a main focus on hair cells. She earned her PhD in Developmental Biology from University of Science and Culture, Tehran, Iran, 2016. As of now she is a principal investigator in Royan Institute and the head of Hair and Skin Research team.

Developmental biology, Wound healing, Hair loss, Skin and hair diseases
We have experience more than one decade in mechanisms regulating and governing adult skin cells and hair regeneration. Our work paved the way for the initiation of some clinical trials in skin related diseases, such as vitiligo, burns, wrinkles, Epidrmolysis Bullosa, and alopecia. What we are trying to do in future is a mix of developmental and stem cell biology, applied to skin and hair diseases. We are interested in the ultimate goal of treating patients.

Farzad alipour (Ph.D student)

Project title: Genetic modification of patient’s skin cell in dystrophic epidermolysis bullosa (EB)

Sara Amjadian (Ph.D student)

Project title: MicroRNA profiling during hypertrophic scar formation created by severe injuries

Mohammadi P, Ebrahimi M, Baharvand H. Corneal differentiation following HSC70 and HSP72 expression in air-exposed limbal stem cells cultured on denuded amniotic membrane. Cell J .2010-12(10) -(173-182)

2.Ebrahimi M, Mohammadi P, Daryadel A, Baharvand H. Assessment of heat shock protein (HSP60, HSP72, HSP90, and HSC70) expression in cultured limbal stem cells following air lifting. Molecular Vision 2010; 16:1680-1688.

3.Taghiabadi E, Mohammadi P, Aghdami N, Falah N, Orouji Z, Nazari A, Shafieyan S. Treatment of Hypertrophic Scar in Human with Autologous Transplantation of Cultured Keratinocytes and Fibroblasts along with Fibrin Glue. Cell J. 2015 Spring;17(1):49-58. Epub 2015 Apr 8.

4.Jalili-Firoozinezhad S, Rajabi-Zeleti S, Mohammadi P, Gaudiello E, Bonakdar S, Solati-Hashjin M, Marsano A, Aghdami N, Scherberich A, Baharvand H, Martin I. Facile fabrication of egg white macroporous sponges for tissue regeneration. Adv Healthc Mater. 2015 Oct 28;4(15):2281-90

5.Nilforoushzadeh M.A, Rahimi Jameh E, Jaffary F, Abolhasani E, Keshtmand G, Zarkob H, Mohammadi P (co-correspond author), Aghdami N. Hair Follicle Generation by Injecting Adult Human Follicular Epithelial and Dermal Papilla Cells in C57BL/6 nude mice. Cell J. 2017 Summer;19(2): Serial Number: 74

6.Mohammadi P, Kass Youssef K, Aghdami N. Human Hair Reconstruction: clos but yet so far. Stem Cells and Development. Stem Cells Dev. 2016 Dec 1;25(23):1767-1779. Epub 2016 Nov 8

7.Shayan Asl N, Nejat F, Mohammadi P, Nekoukar A, Hesam S, Ebrahimi M, Jadidi K. Amniotic Membrane Extract Eye Drop (AMEED) promotes human limbal stem cell proliferation and induces Corneal Epithelium healing in Rabbit model. Cell J. 2019 winter ;20(4): Serial Number: 80

8.Orouji Z, Bajouri A, Ghasemi M1(first authors), Mohammadi P (second author), Fallah N, Shahbazi A, Rezvani M, Vaezi F, Khalajasadi Z, Alizadeh A, Taghiabadi E, Dashtbozorgi S, Aghdani R, Hosseini E, Bahahrvand H, Shafieyan S*, Aghdami N*. A Single-arm Open-Label Clinical Trial of Autologous Epidermal Cell Transplantation for Stable Vitiligo: A 30-month Follow-Up. Journal of dermatological science (in press).

9.Alizadeh S, Aghadmi N, Seyedalipour B, Mohammadi P* (correspond author). Investigation the effect of copper nanoparticles on the toxicity and migration of keratinocyte cells. Tehran University Medical Journal, November 2018; Vol. 76, No. 8: 543-549.

Alizadeh S, Seyedalipour B, Shafieyan S, Kheime A, Mohammadi P* (co-correspond author), Aghdami N. Copper Nanoparticles Promote Rapid Wound Healing in Acute Full Thickness Defect via Acceleration of Skin Cell Migration, Proliferation, and Neovascularization. BBRC Journal. Volume 517, Issue 4, 1 October 2019, Pages 684-690.

Bajouri A, Orouji Z, Taghiabadi E, Nazari A, Shahbazi A, Fallah N, Mohammadi P, Rezvani M, Jouyandeh Z, Vaezirad F, Khalajasadi Z, Ghasemi M, Fanni A, Alizadeh A, Baharvand H, Shafieyan S, Aghdami N. Long-term Follow-up of Autologous Fibroblast Transplantation for Facial Contour Deformities; A Non-randomized Phase IIa Clinical Trial. Cell J. Volume 22, Number 1, Apr-Jun (Spring) 2020, Serial Number: 85.

Mohammadi P, Nilforoushzadeh M.A, Kass Youssef K, Sharifi-Zarchi A, Moradi Sh, Khosravani P, Aghdami A, Taheri P, Hosseini-Salekdeh Gh, Baharvand H, Aghdami N. Defining microRNA signatures of hair follicular stem and progenitor cells in healthy and androgenic alopecia patients. Journal of dermatological science. 6 November 2020 (In press).