Parvaneh Mohammadi Ph.D.

Department of Stem Cells and Developmental Biology

Assistant professor

Parvaneh Mohammadi earned her B. Sc. in Animal Biology from Shahid Chamran University of Ahvaz, Iran in 2006, and also, she graduated in MSc of developmental biology from Science and Culture University, Tehran, Iran, 2009. Upon completion of her Master’s degree, she continued her research as a research assistant at Royan Institute, in the Department of Regenerative Medicine and she started research on skin and hair field. In 2010 she got accepted as a PhD student in the Department of Cell and Developmental Biology at Royan Institute where she thereafter began a series of studies with a main focus on hair cells. She earned her PhD in Developmental Biology from University of Science and Culture, Tehran, Iran, 2016. As of now she is a principal investigator in Royan Institute and the head of Hair and Skin Research team.

Developmental biology, Wound healing, Hair loss, Skin and hair diseases
We have experience more than one decade in mechanisms regulating and governing adult skin cells and hair regeneration. Our work paved the way for the initiation of some clinical trials in skin related diseases, such as vitiligo, burns, wrinkles, Epidrmolysis Bullosa, and alopecia. What we are trying to do in future is a mix of developmental and stem cell biology, applied to skin and hair diseases. We are interested in the ultimate goal of treating patients.

M.Sc Students:

Sanaz Alizadeh (M.Sc. student)

Project title: Effects of copper nanoparticles on the fibroblasts, keratinocytes and vascular endothelial cell function in full thickness wound healing

 

Raheleh Aghdami (M.Sc.)

Project title: In vitro constitution of bioengineered follicle germ and transplantation in patients with androgenetic alopecia phase I clinical trial

Sara Afsharaalam (M.Sc. student)

Project title: Gene delivery of LAMB3 to human keratinocytes as a therapeutic approach of Junctional Epidermolysis Bullosa

 

Hadith Abdollahzadeh (M.Sc. student)

Project title: Comparison of skin transcriptome between cell transplantation responder and non-responder vitiligo patients

Anosheh Tajsharghi (M.Sc.)

Project title: Evaluating the effect of adipose derived mesenchymal stem cell spray on acceleration of wound healing and reduction of scar after meshed skin grafting deep burns

 

Shima Rafiee (MD student)

Project title: Evaluating the effect of adipose derived mesenchymal stem cell spray on acceleration of wound healing and reduction of scar after meshed skin grafting deep burns

Ph.D Students:

Farzad alipour (Ph.D student)

Project title: Genetic modification of patient’s skin cell in dystrophic epidermolysis bullosa (EB)

Sahar Jolodari (Ph.D student)

Project title: Keratin-based hydrogel loaded with LL-37 peptide as a skin substitute for wound healing applications

Ehsan Taghiabadi (Ph.D student)

Project title: Improvement of trichogenic ability of cultured human dermal papilla cells by exosomes

Sara Amjadian (Ph.D student)

Project title: MicroRNA profiling during hypertrophic scar formation created by severe injuries

Selected Publications:

1.Mohammadi P, Ebrahimi M, Baharvand H. Corneal differentiation following HSC70 and HSP72 expression in air-exposed limbal stem cells cultured on denuded amniotic membrane. Cell J .2010-12(10) -(173-182).

2.Ebrahimi M, Mohammadi P, Daryadel A, Baharvand H. Assessment of heat shock protein (HSP60, HSP72, HSP90, and HSC70) expression in cultured limbal stem cells following air lifting. Molecular Vision 2010; 16:1680-1688.

3.Taghiabadi E, Mohammadi P, Aghdami N, Falah N, Orouji Z, Nazari A, Shafieyan S. Treatment of Hypertrophic Scar in Human with Autologous Transplantation of Cultured Keratinocytes and Fibroblasts along with Fibrin Glue. Cell J. 2015 Spring;17(1):49-58. Epub 2015 Apr 8.

4.Jalili-Firoozinezhad S, Rajabi-Zeleti S, Mohammadi P, Gaudiello E, Bonakdar S, Solati-Hashjin M, Marsano A, Aghdami N, Scherberich A, Baharvand H, Martin I. Facile fabrication of egg white macroporous sponges for tissue regeneration. Adv Healthc Mater. 2015 Oct 28;4(15):2281-90.

5.Nilforoushzadeh M.A, Rahimi Jameh E, Jaffary F, Abolhasani E, Keshtmand G, Zarkob H,Mohammadi P (co-correspond author), Aghdami N. Hair Follicle Generation by Injecting Adult Human Follicular Epithelial and Dermal Papilla Cells in C57BL/6 nude mice. Cell J. 2017 Summer;19(2): Serial Number: 74.

6.Mohammadi P, Kass Youssef K, Aghdami N. Human Hair Reconstruction: clos but yet so far.Stem Cells and Development. Stem Cells Dev. 2016 Dec 1;25(23):1767-1779. Epub 2016 Nov.

7.Orouji Z1, Bajouri A1, Ghasemi M1, Mohammadi P , Fallah N, Shahbazi A, Rezvani M, Vaezi F, Khalajasadi Z, Alizadeh A, Taghiabadi E, Dashtbozorgi S, Aghdani R, Hosseini E, Bahahrvand H, Shafieyan S*, Aghdami N*. A Single-arm Open-Label Clinical Trial of Autologous Epidermal Cell Transplantation for Stable Vitiligo: A 30-month Follow-Up. Journal of dermatological science (in press).