Parvaneh Mohammadi Ph.D.
Department of Stem Cells and Developmental Biology
Parvaneh Mohammadi earned her B. Sc. in Animal Biology from Shahid Chamran University of Ahvaz, Iran in 2006, and also, she graduated in MSc of developmental biology from Science and Culture University, Tehran, Iran, 2009. Upon completion of her Master’s degree, she continued her research as a research assistant at Royan Institute, in the Department of Regenerative Medicine and she started research on skin and hair field. In 2010 she got accepted as a PhD student in the Department of Cell and Developmental Biology at Royan Institute where she thereafter began a series of studies with a main focus on hair cells. She earned her PhD in Developmental Biology from University of Science and Culture, Tehran, Iran, 2016. As of now she is a principal investigator in Royan Institute and the head of Hair and Skin Research team.
Developmental biology, Wound healing, Hair loss, Skin and hair diseases
We have experience more than one decade in mechanisms regulating and governing adult skin cells and hair regeneration. Our work paved the way for the initiation of some clinical trials in skin related diseases, such as vitiligo, burns, wrinkles, Epidrmolysis Bullosa, and alopecia. What we are trying to do in future is a mix of developmental and stem cell biology, applied to skin and hair diseases. We are interested in the ultimate goal of treating patients.
Raheleh Aghdami (M.Sc.)
Project title: In vitro constitution of bioengineered follicle germ and transplantation in patients with androgenetic alopecia phase I clinical trial
Sara Afsharaalam (M.Sc. student)
Project title: Gene delivery of LAMB3 to human keratinocytes as a therapeutic approach of Junctional Epidermolysis Bullosa
Shima Rafiee (MD student)
Project title: Evaluating the effect of adipose derived mesenchymal stem cell spray on acceleration of wound healing and reduction of scar after meshed skin grafting deep burns
Farzad alipour (Ph.D student)
Project title: Genetic modification of patient’s skin cell in dystrophic epidermolysis bullosa (EB)
Sahar Jolodari (Ph.D student)
Project title: Keratin-based hydrogel loaded with LL-37 peptide as a skin substitute for wound healing applications
Ehsan Taghiabadi (Ph.D student)
Project title: Improvement of trichogenic ability of cultured human dermal papilla cells by exosomes
Sara Amjadian (Ph.D student)
Project title: MicroRNA profiling during hypertrophic scar formation created by severe injuries
HSP72 expression in air-exposed limbal stem cells cultured on denuded amniotic membrane. Cell J .2010-12(10) -(173-182)
2.Ebrahimi M, Mohammadi P, Daryadel A, Baharvand H. Assessment of heat shock protein (HSP60, HSP72, HSP90, and HSC70) expression in cultured limbal stem cells following air lifting. Molecular Vision 2010; 16:1680-1688.
3.Taghiabadi E, Mohammadi P, Aghdami N, Falah N, Orouji Z, Nazari A, Shafieyan S. Treatment of Hypertrophic Scar in Human with Autologous Transplantation of Cultured Keratinocytes and Fibroblasts along with Fibrin Glue. Cell J. 2015 Spring;17(1):49-58. Epub 2015 Apr 8.
4.Jalili-Firoozinezhad S, Rajabi-Zeleti S, Mohammadi P, Gaudiello E, Bonakdar S, Solati-Hashjin M, Marsano A, Aghdami N, Scherberich A, Baharvand H, Martin I. Facile fabrication of egg white macroporous sponges for tissue regeneration. Adv Healthc Mater. 2015 Oct 28;4(15):2281-90
5.Nilforoushzadeh M.A, Rahimi Jameh E, Jaffary F, Abolhasani E, Keshtmand G, Zarkob H, Mohammadi P (co-correspond author), Aghdami N. Hair Follicle Generation by Injecting Adult Human Follicular Epithelial and Dermal Papilla Cells in C57BL/6 nude mice. Cell J. 2017 Summer;19(2): Serial Number: 74
6.Mohammadi P, Kass Youssef K, Aghdami N. Human Hair Reconstruction: clos but yet so far. Stem Cells and Development. Stem Cells Dev. 2016 Dec 1;25(23):1767-1779. Epub 2016 Nov 8
7.Shayan Asl N, Nejat F, Mohammadi P, Nekoukar A, Hesam S, Ebrahimi M, Jadidi K. Amniotic Membrane Extract Eye Drop (AMEED) promotes human limbal stem cell proliferation and induces Corneal Epithelium healing in Rabbit model. Cell J. 2019 winter ;20(4): Serial Number: 80
8.Orouji Z, Bajouri A, Ghasemi M1(first authors), Mohammadi P (second author), Fallah N, Shahbazi A, Rezvani M, Vaezi F, Khalajasadi Z, Alizadeh A, Taghiabadi E, Dashtbozorgi S, Aghdani R, Hosseini E, Bahahrvand H, Shafieyan S*, Aghdami N*. A Single-arm Open-Label Clinical Trial of Autologous Epidermal Cell Transplantation for Stable Vitiligo: A 30-month Follow-Up. Journal of dermatological science (in press).
9.Alizadeh S, Aghadmi N, Seyedalipour B, Mohammadi P* (correspond author). Investigation the effect of copper nanoparticles on the toxicity and migration of keratinocyte cells. Tehran University Medical Journal, November 2018; Vol. 76, No. 8: 543-549.