Fereshteh Esfandiari Ph.D.

Department of Stem Cells and Developmental Biology

Assistant professor

Email: fereshtehesfandiari@royaninstitute.org

Phone:

CV:Fereshteh Esfandiari CV

About

Fereshteh Esfandiari earned her B. Sc. in Biology from Shiraz University, Shiraz, Iran in 2009. She started her research at Royan institute in 2009 and joined Royan in 2011 as a full-time researcher. She has earned her PhD from University of Science and Culture in 2016 and her current research is focused on in vitro germ cells production/differentiation by engineering approach.

Research interests

  1. Stem cells in Reproductive Biology
  2. Female Reproductive Diseases
  3. Germ Line Development

Group members

MSc Students:

Zohreh Shalchian (PhD student)

Gelareh Mikaeili (M.Sc student)

Reyhaneh Sadat Hayaei (Researcher)

Publications

Selected Publications:

  1. Esfandiari F, Ashtiani MK, Sharifi-Tabar M, Saber M, Daemi H, Ghanian MH, Shahverdi A, Baharvand H. Microparticle-Mediated Delivery of BMP4 for Generation of Meiosis-Competent Germ Cells from Embryonic Stem Cells. Macromol Biosci. 2017 Mar;17(3)
  2. Esfandiari F, Mashinchian O, Ashtiani MK, Ghanian MH, Hayashi K, Saei AA, Mahmoudi M, Baharvand H. Possibilities in Germ Cell Research: An Engineering Insight. Trends Biotechnol. 2015 Dec;33(12):735-746. doi: 10.1016/j.tibtech.2015.09.004. Epub 2015 Oct 20. Review.
  3. Sharifi Tabar M, Hesaraki M, Esfandiari F, Sahraneshin Samani F, Vakilian H, Baharvand H., Evaluating Electroporation and Lipofectamine Approaches for Transient and Stable Transgene Expressions in Human Fibroblasts and Embryonic Stem Cells. Cell J. 2015 Fall;17(3):438-50. Epub 2015 Oct 7.
  4. Attari F, Sepehri H, Ansari H, Hassani SN, Esfandiari F, Asgari B, Shahverdi A, Baharvand H. Efficient induction of pluripotency in primordial germ cells by dual inhibition of TGF-β and ERK signaling pathways. Stem Cells Dev. 2014 May 15;23(10):1050-61. doi: 10.1089/scd.2013.0438. Epub 2014 Feb 20.
  5. Esfandiari F, Fathi A, Gourabi H, Kiani S, Nemati S, Baharvand H. Glycogen synthase kinase-3 inhibition promotes proliferation and neuronal differentiation of human-induced pluripotent stem cell-derived neural progenitors. Stem Cells Dev. 2012 Nov 20;21(17):3233-43. doi: 10.1089/scd.2011.0678. Epub 2012 Aug 10.
  6.  Mirzaeian, Eftekhari-Yazdi P, Esfandiari F, Eivazkhani F, Rezazadeh Valojerdi M, Moini A, Fathi R. Induction of mouse peritoneum mesenchymal stem cells into germ cell-like cells using follicular fluid and cumulus cells conditioned media. Stem Cells Dev. 2019 Feb 15. doi: 10.1089/scd.2018.0149.
  7. Moraveji SF, Esfandiari F, Sharbatoghli M, Taleahmad S, Nikeghbalian S, Shahverdi A, Baharvand H, Optimizing Methods for Human Testicular Tissue Cryopreservation and Spermatogonial Stem Cells Isolation. J Cell Biochem. 2019 Jan;120(1):613-621.
  8. Yekani F, Azarnia M,  Esfandiari F, Hassani SN,  Baharvand H, Enhanced development of mouse single blastomeres into blastocysts via the simultaneous inhibition of TGF‐β and ERK pathways in microdroplet culture. J Cell Biochem. 2018 Sep;119 (9):7621-7630.
  9. Yekani F, Fazel-Tabar M, Kowsari-Esfahan R, Renaud P, Kavand H, Esfandiari F, Azarnia M, Montazeri L, Baharvand H. Enhancing developmental rate and quality of mouse single blastomeres into blastocysts using a microplatform. J Cell Physiol. 2018Dec;233 (12):9070-9076.
  10. Raha Favaedi, Heidar Heidari Khoei, Fereshteh Chitsazian, Simin Yari, Abbas Piryaei, Hossein Baharvand, Hugo Vankelecom, Firouzeh Ghafari, Maryam shahhoseini*, An insight to epigenetics of human endometriosis organoids: DNA methylation analysis of HOX genes and their co-factors, Fertility & Sterility August 2020.
  11. Heidari H#., Esfandiari F#, Piryaei A., Rivron N. Baharvand H. Organoid technology in female reproductive biomedicine. Reproductive Biology and Endocrinology 2020.
  12. Bahrehbar Kh, Rezazadeh Valojerdi M, Esfandiari F, Fathi R, Hassani SN, Baharvand H, Human Embryonic Stem cells–derived Mesenchymal Stem Cells Restore Ovarian Function and Rescue Fertility in Mouse Model of Chemotherapy-Induced Premature Ovarian Failure, The World of Stem Cells 2020.
  13. Moraveji SF, Esfandiari F, Taleahmad S, Nikeghbalian S, Masoudi SN, Shahverdi A, Baharvand H, Suppression of transforming growth factor-β signaling enhances spermatogonia proliferation and spermatogenesis recovery following chemotherapy, Human Reproduction 2020.
  14. Javadi A, Mokhtari S, Moraveji SF, Gouarbi H*, Esfandiari F*, Short Time Exposure to Low Concentration of Zinc Oxide Nanoparticles Up-regulates Self-renewal and Spermatogenesis-Related Gene Expression. The International Journal of Biochemistry & Cell Biology 2020.
  15. Saber M, Hayaei R, Sayahpour F, Esfandiari F*, In Vitro Cytotoxicity of Zinc Oxide Nanoparticles in Ovarian Germ Cells. Toxicology in vitro 2020.
  16. Moraveji SF, Esfandiari F*, Sharbatoghli M, Taleahmad S, Nikeghbalian S, Shahverdi A, Baharvand H, Optimizing Methods for Human Testicular Tissue Cryopreservation and Spermatogonial Stem Cells Isolation. J Cell Biochem. 2019 Jan;120(1):613-621.
  17. Mirzaeian L, Eivazkhani F, Hezavehei M, Moini A, Esfandiari F, Rezazadeh M, Fathi R, Optimizing the cell seeding protocol to human decellularized ovarian scaffold: application of dynamic system for bio-engineering, Cell J. Volume 22, Number 2, Jul- Sep (Summer) 2020 , Serial Number: 86

Open position

Currently, I have no open position.