Sara Pahlavan Ph.D. Stem Cells and Developmental Biology Assistant professor
Email:sarapahlavan@royaninstitute.org Tel:+98 21 23562512 Fax: CV:Sara-Pahlavan-CV-2024.pdf
Sara Pahlavan is a member of Royan Cardiovascular Group. She studied Biology in her B.Sc and graduated in M.Sc of Physiology from Shiraz University. During her undergraduate studies, she got interested in physiology of cardiac cells, specifically excitation-contraction coupling. To pursue her interest, she moved to Germany and started her graduate studies in Professor Peter Lipp’s lab at Universitäts Klinikum des Saarlandes. There, she learned state of the art technologies such as simultaneous “patch-clamp” and “Ca2+ imaging” to study excitation-contraction coupling in cardiomyocytes. Furthermore, she used transgenic mice to study pathophysiology of inherited cardiac diseases with respect to electrophysiology and/or Ca2+ machinery. Toward the end of her PhD studies, she got interested in using patient-specific iPSC-derived cardiomyocytes to study cardiac disease in human cardiac cells and to test new drugs. To pursue this goal, she moved to United States and started her postdoctoral fellowship in Professor Martin Morad’ lab at Medical University of South Carolina. There she could develop a new genetically-encoded Ca2+ probe to study Ca2+ induced Ca2+ release and Ca2+ sparks in cardiomyocytes of healthy and patient-specific iPSC-derived cardiomyocytes. She joined Royan Institute at 2015 and currently she works as an Assistant Professor in cardiovascular Group.
PhD Alumni
MSc Alumni
MD-PhD student
Safety and Feasibility of Intracoronary Transplantation of Allogenic Wharton’s Jelly Derived-Mesenchymal Stem Cells (WJ-MSCs) in Pediatrics with Non-Ischemic Dilated Cardiomyopathy (PNIDCM): Clinical Trial Phase I
MSc Students
The study of angiogenesis potential and cardiomyocyte maturation in cardiac microtissue after heterotopic transplantation onto Chorioallantoic membrane
Investigation into the maturation of neonatal rat cardiomyocytes by metabolic shift from glycolysis to oxidative phosphorylation by targeting SIRT3
Studying the effect of PDMS micropatterns on the maturation of neonatal rat cardiomyocytes
The study of the effect of U266 secretome- or hypoxia-preconditioned mesenchymal stem cells conditioned medium on angiogenesis of in vitro generated cardiac microtissue
Former Research assistant