Massoud Vosough MD. Ph.D. Regenerative Medicine
Email:masvos@royaninstitute.org Tel:+982122518388 Fax: CV:CV-Massoud-Vosough5-1.pdf
Massoud Vosough is medical professional with a diverse background in the regenerative medicine field. After graduating from Tehran University of Medical Sciences with a degree in general medicine, he continued his studies and specialized in his current profession Starting in 2006, Dr. Vosough studied medical biotechnology, pursuing a doctorate at the Pasteur Institute of Iran. His research focus culminated in thesis on the “mass production of liver cells in a bioreactor, utilizing both embryonic and induced stem cells”, which was conducted at Royan Research Institute. After successfully defending his thesis, Massoud passed two consecutive postdoctoral courses at Karolinska Institute in Sweden, where he worked under the guidance of Professor Stefan Strom. During this period, he contributed to the HUMAN project in the European Union and various other projects in the realm of regenerative medicine. Presently, Massoud is the head of the Regenerative Medicine Department and Head of the Cell Therapy Center at Royan Research Institute. His current research focuses on the control of gastrointestinal and liver diseases, with a primary focus on utilizing stem cells for the treatment of chronic and degenerative conditions. Dr. Massoud Vosough’s dedication to advancing medical knowledge and contributions to the forefront of regenerative medicine showcase his passion for making a lasting impact in this field.
PhD students
Liver fibrosis in vitro modeling by co-culture of liver parenchymal and non-parenchymal cell lines in liver extracellular matrix-derived hydrogel, for drug evaluation
Application of HNF4α-specific lncRNA to Improve Metabolic Performance of Cancerous Hepatic Micro-Tissues
Anti-fibrotic impact of adiponectin-enriched ECM on activated Hepatic Stellate Cells in a Liver 3D model
Modulation of Mitochondrial Autophagy using Resveratrol-loaded nano-carriers in Hepatocellular Carcinoma Cells: In Vitro and Mouse Model
C-Flip/Ku70 complex manipulation via EGCG-loaded niosomes in order to cell viability and cancerous phenotype evaluations in hepatocellular carcinoma cells in vitro and in vivo
Evaluating anticancer effects of Turmerone-loaded niosomes on hepatocellular carcinoma model
PhD Alumni
MSc Alumni
MSc Students
Evaluation of anti-aging effects of HPE on normal human dermal fibroblast
The effect of changing the expression of KDM6A on cancerous features in hepatocellular carcinoma cell line
The impact of treatment with Retinoic acid on fibrogenic properties of activated hepatic stellate cells through crosstalk with Hedgehog signaling
Simultaneous inhibition of WNT/β-catenin and TGF-β signaling pathways by IWP-2 and SB431542 small molecules in order to reduce cancerous potential of hepatocellular carcinoma cell line, Hep3B
Apoptosis Induction by Resveratrol-loaded Poly Lactic-co-Glycolic Acid micro-particles in 3D Model of Hepatocellular Carcinoma
The impact of vitamin E-mediated Nrf2 signaling pathway activation in an in vitro biomimetic non-alcoholic fatty liver disease model fabricated from Huh-7 and LX-2 cells co-culture on liver extracellular matrix
The Impact of the ECM`s Collagen Type I Content Extracted from Rat Tail on Fibrogenic Features of Activated Liver stellate cells in vitro.
Postdoctoral fellow
Evaluation of the effect of hsa-miR-30b-3p treatment on LDL uptake in hepatocytic cells through specific targeting of PCSK9, APOB and CETP genes